Intravenous Immunoglobulin Versus Anti-D Immunoglobulin: When Better Treatment May Not Be the Best Treatment

comparison of intravenous immunoglobulin (ivig) and intravenous anti-d for treatment of acute idiopathic thrombocytopenic purpura

introduction: acute idiopathic thrombocytopenic purpura (itp) is an autoimmune bleeding disorder of childhood caused by production of auto antibodies against platelets. the aim of the present study was to compare the efficacy of intravenous immunoglobulin (ivig) and intravenous anti-d(iv anti-d) in itp treatment. methods and materials: in a clinical trial, 43 children with acute itp referred to...

Uses of intravenous immunoglobulin

Adjuvant high dose IVIgs are being used increasingly in a range of immune-mediated and auto-immune diseases. Although numerous immunomodulatory mechanisms have been suggested, the exact mechanisms of action are poorly understood. The efficacy of IVIg in certain diseases has been proven in clinical trials, in so far as IVIg is approved as the therapy of choice for Kawasaki syndrome and idiopathi...

Treatment of human immunodeficiency virus-related thrombocytopenia with intravenous anti-rhesus D immunoglobulin.

SIR-The recent paper by Glatt and Anand [1] provides an excellent, comprehensive review of the natural history and treatment options with regard to HIV-related thrombocytopenia. We wish to discuss the efficacy of therapy with intravenous anti-rhesus D (Rho[D]) immunoglobulin in this setting. Glatt and Anand state that the drawbacks to intravenous anti-RHo(D) include lack of experience with its ...

Intravenous immunoglobulin treatment in neurological diseases.

Retinal vein occlusion following intravenous immunoglobulin treatment.

Intravenous immunoglobulin (IVIg) is concentrated human immunoglobulins made from pooled donor plasma. Commercial preparations were used for clinical administration since early 1980s [1]. It modulates the immune response in a variety of inflammatory and autoimmune disorders. Although high-dose IVIg generally is considered safe, it is not without side effects and may promote life-threatening thr...